Where and what sort of temperatures are you going to be riding in?
Majority of what I get to ride is dog mushing trails or snowmachine trails up here. Snowmachines suck, they make all sorts of ups and downs on what could be a flat trail. Here in Fairbanks Alaska, you will usually see 9:Zero:7, Fatback, Trek, and Salsa branded fat bikes. Not saying that any is better than the other, just that's what we all tend to use and work up here. I personally ride a 9:Zero:7 Tundra from a couple of years ago, fully rigid, 1x12 GX drivetrain, Dillinger 5 tires with tubes. No particular reason why I didn't go tubeless except that I've never had a flat and thus never felt the need to change it. As you might imagine, not all fatbike tires are created equal, 45NRTH Dillinger 4 or 5 is the go to tire up here in either studded or studless versions. When I upgraded to my Dillenger 5's from the Jumbo Jims that came on my bike.. oh my god it was life changing for how much better my bike performed on the trail. Check with the locals as to if studs are really needed or not, if you have icy conditions, overflows, or lots of swamp/pond crossings like I do then studded tires are worth the extra expense.
My primary advice is to keep the bike simple, reliable, and maintained. At least where I ride, a broken bike or mechanical problem can lead to serious and potential life threatening conditions quite rapidly. You will have 4"-5" tires to help soak up small bumps and vibrations and forgoing a suspension fork will save weight and complications on the trail. Definitely splurge on carbon bars and foam grips, it helps cut down the cold transfer to your hands compared to alloy bars and regular grips.
Second bit of advice. Get poagies. Winter gloves suck keeping your hands warm on a bike in the winter and are impossible to manipulate shifters and brakes with. A set of poagies plus your summer gloves or liner gloves works phenomenal. Today's ride was at -31*f and I had a set of winterweight Handup gloves inside my Dogwood Designs poagies (local company). Hands were perfect temps.
Lastly, if you plan on riding at night in the winter, invest in good lights (for that matter if you ever ride at night you should have good lights.). You do not want to have a lighting failure in a cold dark winter ride. Stuff from Lupine lighting, Light and Motion, and Outbound Lighting get used a lot up here.