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Long COVID?

RoninSkier

Getting off the lift
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259
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Calgary, AB, Canada
Some news regarding new Omnicron mutation subvariant on the increase.
A bit concerning. Anyone get it or know someone who got it? What and how bad were symptoms?
 

Pequenita

Making fresh tracks
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Aug 5, 2017
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Some news regarding new Omnicron mutation subvariant on the increase.
A bit concerning. Anyone get it or know someone who got it? What and how bad were symptoms?
I know several people who have gotten Covid (again) in the last week or two, but I don't think they know whether it's the latest subvariant. Both had to take a day or two off from work due to high fevers and all over body aches. They are in their 30s and 40s (I think).

FYI re: long covid - this popped up in my in box today: https://covid19.nih.gov/news-and-stories/nih-launches-clinical-trials-long-covid-treatments
 

RoninSkier

Getting off the lift
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Calgary, AB, Canada
I know several people who have gotten Covid (again) in the last week or two, but I don't think they know whether it's the latest subvariant. Both had to take a day or two off from work due to high fevers and all over body aches. They are in their 30s and 40s (I think).

FYI re: long covid - this popped up in my in box today: https://covid19.nih.gov/news-and-stories/nih-launches-clinical-trials-long-covid-treatments
Thxs for this. This was needed 2yrs ago. Better late than even later.
 

scott43

So much better than a pro
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Great White North
Some news regarding new Omnicron mutation subvariant on the increase.
A bit concerning. Anyone get it or know someone who got it? What and how bad were symptoms?
I've read it's more of the same, nothing indicating it's any more concerning than Omicron. Other than it has a better chance of evading existing antibodies.
 

RobSN

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Prescott Valley, AZ
I just got Covid 2½ weeks ago in the UK. Unknown variant. I'm previously quadruple vaccinated. Dry - and still lingering - cough, sweats for first 2 days, mild headache possibly from coughing, and an overall feeling of just blah but it all other than the lingering cough went away after about 4 days - and frankly no worse than a nasty cold and better than the last flu I had which was years ago. No loss of taste or smell. I'd have been mildly interested to have known the variant, but I don't ...
 

James

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The interest in what varient is odd. Unless someone has had their swab sequenced, you wouldn’t know. It’s only a probability given general sequencing in the area. The UK was much more on top of that during the pandemic.

No other virus do people want to know the variant. It’s mostly media driven and there’s lots of disinformation. Like back in late 2020- “it’s less virulent”. No, people are still dying. “Spreads easier” - almost certainly due to public behaviors. I.e., more people in close contact, not sheltering. It’s very difficult to show differences in contagiousness with behavior eliminated.

@RoninSkier , did you get vaccinated back whenever?
The Paxlovid trial would probably be worth getting into if no contraindications. You could get the placebo, but if they find it works conclusively during the study, I would think they have to give it to you.
 

salvatore

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Glad I stumbled on this thread.

I've had COVID four times: 2/24/2020, 9/29/2021, 3/17/2022, and 11/19/22.

The first time I thought I was a goner (but of course, had barely even heard of COVID back then), second time not bad, third time sucked, fourth time mild. Nevertheless, many of the symptoms and side effects have been rough and incredibly persistent.

To this day I have recovered only about 50% of my taste and smell. Lots of body aches, shortness of breath, memory loss, vision impairment, weight gain, constant malaise-like feeling (sort of like having a low-grade fever a lot of the time), some blood sugar issues, several months of excruciating joint pain.

Just saw my doc today, and he and I talked quite a bit about this very subject... hence why the thread caught my eye this evening! It was such an incredible relief to hear him say that while he has no evidence, it is very likely that my body is really messed up from my immune response to COVID along with an adverse reaction to the vaccine (which triggered many of these symptoms, especially the incredible fatigue). What to do about it, of course, is the question. He recommended I try to get in a long-covid study, which I'm looking into right now.

I appreciate all the info and am still working through this entire thread...
 

Pequenita

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The Paxlovid trial would probably be worth getting into if no contraindications. You could get the placebo, but if they find it works conclusively during the study, I would think they have to give it to you.
I wouldn't make that assumption. I did a more than superficial dive on Pax last night for an unrelated issue, and right now prescribing it to treat long COVID is an off label use. I'm not sure they can give it to someone in the long COVID trial who received the placebo, even if the trial had good results.
 

Pequenita

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What did I just read/hear . . . Something about metformin and long Covid, I think.

Oh, this - https://covid19.nih.gov/news-and-stories/can-diabetes-treatment-reduce-risk-long-covid#:~:text=Metformin, a treatment for type,of more than 1,100 people.

Heard on NPR within the last couple of days. Haven’t read this, know nothing about it, just remembered I heard it.
Huh. I wonder what happens if it's already part of one's regular medications, and then they get covid...
 

James

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I'm not sure they can give it to someone in the long COVID trial who received the placebo, even if the trial had good results.
The issue is that if a drug is shown to be an effective treatment to the disease, it’s then unethical to continue giving people placebos. So the trial would be stopped, unmasked, and those given placebos would get the drug.

But when/how/if that happens is beyond me, but I think it has to be spelled out in the trial agreement.
 

geepers

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May 12, 2018
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Wanaka, New Zealand
Interesting info on blood clots and long COVID...


This has been discussed for some time now. There's medical trials in various countries.

We've no idea if it was this or something else but the wife has made good progress with some non-prescription, anti-clotting supplements and a gradual build-up of activity load. Nowhere near pre-covid energy levels but the wife today compared with 10-12 weeks ago is chalk and cheese.
 

James

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Paper in Nature on study of VA patients over 2 years post covid.

————————
…We built a cohort of 138,818 individuals with SARS-CoV-2 infection and 5,985,227 noninfected control group from the US Department of Veterans Affairs and followed them for 2 years to estimate the risks of death and 80 prespecified postacute sequelae of COVID-19 (PASC) according to care setting during the acute phase of infection…

Within the 80 prespecified sequelae, 69% and 35% of them became not significant at 2 years after infection among nonhospitalized and hospitalized individuals, respectively…
———————

Pdf-
 

RoninSkier

Getting off the lift
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Jul 12, 2022
Posts
259
Location
Calgary, AB, Canada
The interest in what varient is odd. Unless someone has had their swab sequenced, you wouldn’t know. It’s only a probability given general sequencing in the area. The UK was much more on top of that during the pandemic.

No other virus do people want to know the variant. It’s mostly media driven and there’s lots of disinformation. Like back in late 2020- “it’s less virulent”. No, people are still dying. “Spreads easier” - almost certainly due to public behaviors. I.e., more people in close contact, not sheltering. It’s very difficult to show differences in contagiousness with behavior eliminated.

@RoninSkier , did you get vaccinated back whenever?
The Paxlovid trial would probably be worth getting into if no contraindications. You could get the placebo, but if they find it works conclusively during the study, I would think they have to give it to you.
I am quad vaxed. Unfortunately, only after I got Delta and thought I was recovering.

Then long COVID hit compounding damage from Delta - scared lungs + heart valve damage + other issues.

I focus on NIH PubMed & other resources for medical info. But do scan the news every day like everyone else.

The nature of viruses is to mutate. The interest in variants is only to be aware how severe it may be.

I am waiting for the next vaccine, which is being updated to address all the variants & sub-variants.
 

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